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Australian Journal of Pharmacy : February 2005
When it comes to firmness and satisfactionViagra provides grrrrreat results. When it comes to erectile dysfunction patients first and foremost want a therapy they can rely on to be effective. In a report on 3, 52-week studies published in the Journal of Impotence Research1 (ref. graph), Viagra provided clinically significant improvements in the quality of erections. This 88% improvement in erection quality led to an equally significant improvement in the patients overall satisfaction with their sex life.1 Putsimply, Viagra offers better erections for better sex. ming back for Viagra? Because it works.1,2 (sildenafil/Pfizer) ® Baseline and end-of-study scores for the Sexual Function Questionnaire (SFQ).1 Untreated End of study Firmness of erection n = 638 Satisfaction with sex life n = 634 0 Adapted from Steers et al.1 In three, 52-week flexible dose studies, 671 men were treated with VIAGRA (25mg, 50mg, 100mg). Efficacy was assessed using the Sexual Function Questionnaire. *Scores for all questions ranged from 1 (the worst response) to 5 (the best response). End-of-study scores were determined after 52 weeks of treatment with sildenafil. 1 2.1 2.2 2 88% improvement 81% improvement 4.0 3.9 3 Mean domain scores 4 5 Precautions: combination with other therapies for erectile dysfunction, left ventricular outflow obstruction (e.g. aortic stenosis, hypertrophic obstructive cardiomyopathy), multiple system atrophy, anatomical deformation of the penis (e.g. angulation, cavernosal fibrosis or Peyronie’s disease), predisposing conditions for priapism (e.g. sickle cell anaemia, multiple myeloma, leukaemia), bleeding disorders, active peptic ulceration, diabetic retinopathy, pregnancy, lactation, driving/operating machinery. Adverse reactions: headache, flushing, dyspepsia, nasal congestion, urinary tract nfection, abnormal vision, diarrhoea, dizziness, rash. Dose: initially 50 mg oral dose one hour before sex, increased to 100 mg or reduced to 25 mg based on efficacy and tolerability. Maximum one dose in 24 hours. Reduced dose in elderly, hepatic or renal impairment, with concomitant inhibitors of CYP 3A4. Pfizer Australia Pty Limited, ABN 50 008 422 348, 38–42 Wharf Road, West Ryde NSW 2114. References: 1. Steers W et al. Int J Impot Res 2001;13:261-67. 2. Goldstein I et al. N Eng J Med 1998;338:1397-1404. www.pfizer.com.au ®Registered trademark of Pfizer Inc. 01/05 PFXVI5956.